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27 maj 2021 · Uploaded by Hans Eichorst on May 27, 2021. Get your PERKELES ready, we're going to war, the winter war.
This is a visual tool created to show the progress of SCA2 therapies that are currently being developed. Along the right side of the diagram, treatments are grouped by their mechanism, or how the drug works. The top of the diagram shows the stage of research where the drug is in development.
23 paź 1998 · Spinocerebellar ataxia type 2 (SCA2) is characterized by progressive cerebellar ataxia, including nystagmus, slow saccadic eye movements, and in some individuals, ophthalmoparesis or parkinsonism. Pyramidal findings are present; deep tendon reflexes are brisk early on and absent later in the course.
SCA2 is caused by a genetic mutation that is passed on from parents to their children. In SCA2, the impairment of nerve cells and nerve fibers causes degeneration of the cerebellum (the coordination center of the brain) and related brain regions.
15 wrz 2023 · Spinocerebellar ataxia (SCA) is an inherited (autosomal dominant), progressive, neurodegenerative, and heterogeneous disease that mainly affects the cerebellum. SCA is a subset of hereditary cerebellar ataxia and is a rare disease.
13 gru 2022 · Spinocerebellar ataxias comprise a large and expanding group of diseases characterized by degeneration of the spinal cord and cerebellum. There are 50 individual spinocerebellar ataxias (as of December 2022) 2 referred to sequentially as SCA1, SCA2, ... in order of their discovery and genetic characterization.
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