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  1. Irrespective of whether a wound is surgically induced or caused by trauma, the general healing process of a wound is the same. The wound goes through three overlapping phases of: haemostasis and inflamma-tion, proliferation, and maturation and remodelling (Table 1). Fig 1 shows a tarsal skin wound undergoing the first phases of wound healing.

  2. Skin viability is clinically assessed by colour, warmth, pain sensation and bleeding. Non-viable necrotic skin is black or white and may be non-pliable, cool and devoid of sensation; normal skin is warm, pliable and pink with pain sensation, while questionable areas are blue or purple and sensation is poor.

  3. It is characterized by vasoconstriction (5–10 minutes), followed by vasodilation to allow entry of fluid and cells. Leukocytes kill bacteria, phagocytize debris, and recruit other secondary mediators to help with healing.

  4. 21 paź 2021 · The first action in this phase is vaso-constriction due to the release by endothelial cells of catecholamines (epinephrine and norepinephrine) and prostaglandins.5,6 The primary role of vasoconstriction is to decrease blood loss from the wound, but this is reversed to a vasodilatory state within minutes to allow for the influx of platelets, and ...

  5. 15 wrz 2017 · The injured endothelial cellular membrane releases phospholipids that are transformed into arachidonic acid and its metabolites that mediate vascular tone and permeability. Peripheral vasoconstriction, lasting 5–10 minutes, limits bleeding but simultaneously starves the surrounding tissues of oxygen and nutrients normally carried by the blood.

  6. Title: Atlas of small animal wound management and reconstructive surgery / Michael M. Pavletic. Description: Fourth edition. | Hoboken, NJ : Wiley, 2018. | Includes bibliographical references and index. | Identifiers: LCCN 2017058950 (print) | LCCN 2017060302 (ebook) | ISBN 9781119267515 (pdf) |

  7. A skin flap is portion of skin moved from one area of the body to another with an intact vascular attachment to its donor site. Properly developed flaps survive because of their intact circulation. The loose, elastic skin over the head, neck and trunk in dogs & cats, plus the presence of direct cutaneous arteries make pedicle grafts common and ...