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How should alcoholic patients with Wernicke-Korsakoff Syndrome receive thiamine replacement? The current standard of treatment for such patients is to give them thiamine 100 mg intravenously (IV) before administering glucose containing IV fluids and then to continue this dose for several days.
4 kwi 2022 · Wernicke-Korsakoff syndrome is an unusual type of memory disorder due to a lack of thiamin (vitamin B1) requiring immediate treatment. It most often happens in people with alcohol use disorder and malnutrition.
26 cze 2023 · Wernicke-Korsakoff syndrome is a common complication of a thiamine deficiency that is primarily seen with alcoholics. This syndrome was classically described as a clinical triad consisting of altered mental status (i.e., confusion or dementia), nystagmus (or ophthalmoplegia), and ataxia.
Doses ranged from 100 to 1500 mg intravenous thiamine and up to 300 mg IM thiamine, with no apparent difference in patient outcomes. All patients who received thiamine experienced symptom improvement, and adverse drug events were minimal.
• To assess the efficacy of thiamine in preventing and treating the manifestations of WKS due to excess alcohol consumption. • To determine the optimum form, dose and duration of thiamine treatment for this indication.
12 kwi 2011 · MRI should be used to support the diagnosis of acute WE in patients both with and without alcoholism. Thiamine is indicated for the treatment of suspected or manifest WE, and should be ...
3 gru 2018 · CeDAR nurse Gene Shiling developed a protocol to give vitamin B1 to alcohol users to prevent a type of brain damage called Wernicke encephalopathy. It’s vitamin B1, or thiamine, a substance that plays a key role in converting the foods we eat into energy.
