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  1. www.contraline.comContraline

    Contraline is developing ADAM™, the world’s first implant designed to provide men with long-lasting contraception. It's like the IUD, for men. Learn about how ADAM™ works.

    • Product

      Non-hormonal. Say goodbye to systemic side-effects. Quick....

    • Trials

      Non-hormonal male contraceptive implanted at Epworth...

    • Mission

      Hormonal and. may be painful. Daily obligation and adverse...

    • Team

      Dr. Michael King is a professor of practice in the...

    • Careers

      Diverse group of interesting, caring, and successful people....

    • News

      Over 750 men have been dosed with NEST across Phase 1 and 2...

  2. 5 cze 2024 · It uses two hormones: nestorone, a progestin, and testosterone, the male sex hormone. The nestorone suppresses the production of testosterone in the testes and, with it, the development of...

  3. 20 cze 2024 · The ADAM implant is being marketed as an IUD for men. Experts explain how it really works, and why it might lead to more equitable contraception.

  4. 10 lis 2022 · On Thursday, medical device company Contraline became the first to implant a hydrogel-based male contraceptive into humans in a clinical trial. The reversible, nonhormonal gel was implanted into...

  5. 4 sty 2024 · Doctors have now implanted the hydrogel into 23 men. Next month, after two more men undergo the procedure, Contraline’s first in-human efficacy trial will reach its full enrollment at 25 patients.

  6. 25 kwi 2023 · The second type of IUD is the hormonal IUD, which releases a small amount of levonorgestrel, which is a type of progestin, each day which both thickens cervical mucus, and prevents ovulation. These two actions prevent sperm from fertilizing an egg and therefore prevent pregnancy.

  7. 14 sty 2024 · The idea of adding male hormones to suppress spermatozoa may seem surprising. To understand how it works, it is necessary to take a look at the physiology. It all starts with the hypothalamus.