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  1. Acute or progressing liver involvement is generally related to viral hepatitis reactivation, concomitant autoimmune liver disease, or drug-induced alteration. It is important to screen patients for HBV and HCV infection, to avoid life-threatening reactivations.

  2. Liver function tests (LFT) (i.e. aspartate and alanine aminotransferase [AST, ALT], gamma-glutamyl transpeptidase [gamma-GT], alkaline phosphatase [ALP] and total bilirubin) were analysed at disease onset in therapy-naïve patients and during remission in patients with granulomatosis with polyangiitis (GPA, n = 67), microscopic polyangiitis ...

  3. 31 sie 2024 · Granulomatosis with polyangiitis (GPA), formerly known as Wegener's granulomatosis, is a necrotizing vasculitis affecting small to medium-sized vessels. GPA is part of a spectrum of disorders known as antineutrophil cytoplasmic antibody (ANCA)–associated vasculitides.

  4. Granulomatosis with polyangiitis (GPA), previously known as Wegener's granulomatosis (WG), [1] [2] [3] [4] [5] after the German physician Friedrich Wegener, is a rare long-term systemic disorder that involves the formation of granulomas and inflammation of blood vessels (vasculitis).

  5. 30 lis 2022 · Granulomatosis with polyangiitis is an uncommon disorder that causes inflammation of the blood vessels in your nose, sinuses, throat, lungs and kidneys. Formerly called Wegener's granulomatosis, this condition is one of a group of blood vessel disorders called vasculitis.

  6. Granulomatous liver disease is a common problem and often provides a clue to the presence of underlying systemic disease. Findings of hepatic granulomata on liver biopsy often confuse the clinician and consultant. Granulomatous liver disease may present with an abnormal liver panel but no symptoms.

  7. Wegener s granulomatosis with granulomatous liver involvement. Clin Exp Rheumatol. 2010 Jan-Feb;28 (1 Suppl 57):88-9. Authors. Konstanze Holl-Ulrich 1 , Monika Klass. Affiliation. 1 Institute of Pathology, University Hospital Schleswig-Holstein, Campus Lubeck, Germany. holl-ulrich@patho.uni-luebeck.de. PMID: 20412710. Abstract.

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