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  1. Surgical closure of VSDs is safe; the mortality rate is less than 3%. The long-term outlook following surgery in both the early era 17 and more recent times 18 is generally good with rare residual shunts, frequent right bundle branch block, occasional pulmonary hypertension, infrequent heart block or sinus node dysfunction, and modest ...

  2. 23 wrz 2020 · Overall, 53% of patients with surgically closed VSDs were initially discharged at age <10 years (median age, 6.5 years; range, 2–8 years) and 47% were ≥10 years (median age, 19 years; range, 14–53 years).

  3. The study found that the overall spontaneous closure rate for VSDs was 55%, with an estimated 42% closed within the 1 st year and 70% by age 6 years.

  4. 14 kwi 2024 · Ventricular septal defects (VSDs) are the most common congenital cardiac anomaly in children and are the second most common congenital abnormality in adults, surpassed only by a bicuspid aortic valve.

  5. 24 lis 2022 · Stratified by era of VSD diagnosis, the HR for mortality was 3.2 (95% CI: 2.8–3.7) for unrepaired patients diagnosed before 1990 and 2.4 (95% CI: 2.0–2.7) for patients diagnosed later. Cardiac-related death was the commonest cause of death among unrepaired (30%) and surgically closed (65%) patients. Conclusion.

  6. 14 lis 2006 · Ventricular septal defect (VSD) is a common congenital heart defect in both children and adults. Management of this lesion has changed dramatically in the last 50 years. Catheter-based therapy for VSD closure, now in the clinical trial phase, is another step in the evolution of treatment for this disorder.

  7. 2 lut 2023 · The researchers extracted data for all cases of VSD diagnosed from 1977 to 2018 and compared the life expectancy of 9,136 people with VSD with that of an age- and sex-matched control group of 90,823 people without congenital heart disease. Life expectancy reduced by 10 years.

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