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The condition was variously named by investigators as uVIN, VIN2/3 or high-grade VIN. Five RCTs evaluated medical treatments (imiquimod, cidofovir, indole-3 carbinol), and six studies (one RCT and five NRSs) evaluated surgical treatments or photodynamic therapy.
21 gru 2023 · Surgical management is needed for differentiated vulval intraepithelial neoplasia. Learning objectives. To understand the clinical, histological, and pathological classification of squamous intraepithelial lesions and diagnostic challenges.
Because of the potential for occult invasion, wide local excision should be performed if cancer is suspected, even if biopsies show vulvar HSIL. When occult invasion is not a concern, vulvar HSIL (VIN usual type) can be treated with excision, laser ablation, or topical imiquimod (off-label use).
uVIN/HSIL and d-VIN are treated to reduce the risk of developing invasive cancer and to alleviate symptoms. What treatments are available for uVIN/HSIL? The aim is to remove all affected tissue with a margin of apparently unaffected tissue.
24 lip 2023 · VIN 2 and VIN 3 are both considered high grade and have a higher risk of developing into cancer than low grade VIN. However, treatment can resolve VIN 2 and stop cancer from developing.
29 mar 2023 · Vulval intraepithelial neoplasia or VIN is when abnormal cells develop in the top layer of skin covering the vulva. It is not vulval cancer but could turn into cancer. This may take many years.
18 maj 2019 · For young women with persistent visible lesions, the treatment of choice is CO 2 laser vaporization with an excisional procedure for confirmation of diagnosis.
