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  1. Variola virus forms the characteristic pus-filled pustules and centrifugal rash dis-tribution in the infected patients while trans-mission occurs mainly through respiratory droplets during the early stage of infection. No antiviral drugs are approved for variola virus till date.

  2. Smallpox is an acute, contagious disease caused by the variola virus, a member of the genus Orthopoxvirus, in the Poxviridae family (see the image below). Virologists have speculated that it...

  3. Variola Virus. Variola is a human-specific virus. Generally it can be readily distinguished from other orthopoxviruses capable of infecting man (vaccinia, cowpox, monkeypox) by the characteristic small white pocks produced on the chorioallantoic membrane of developing 12-to 15-day-old chick embryos and the ceiling temperature of growth. How ...

  4. www.biointeractive.org › classroom-resources › virus-explorerVirus Explorer - BioInteractive

    3 sie 2016 · This interactive module explores the diversity of viruses based on structure, genome type, host range, transmission mechanism, replication cycles, and vaccine availability. The Click & Learn incorporates engaging 3D models of 10 different viruses — coronavirus, rabies, influenza A, HIV, Ebola, tobacco mosaic virus (TMV), adenovirus, T7, ...

  5. This is a transmission electron microscopic (TEM) image of a tissue section containing variola virus particles, the pathogen responsible for causing smallpox in humans. These organisms display an internal, dumbbell-shaped structure that represents the viral core containing the viral DNA.

  6. Since variola virus is a pathogen that is uniquely adapted to cause severe, widespread human illness, it is highly likely that it has evolved to specifically thwart an effective immune response to infection.

  7. 8 sie 2023 · Smallpox is the first human infectious disease to be successfully eradicated worldwide. It remains of clinical concern because of the potential for release and weaponization. Smallpox is a member of the viral family poxvirus, genus orthopoxvirus, and species variola virus.