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Variola virus forms the characteristic pus-filled pustules and centrifugal rash dis-tribution in the infected patients while trans-mission occurs mainly through respiratory droplets during the early stage of infection. No antiviral drugs are approved for variola virus till date.
Since variola virus is a pathogen that is uniquely adapted to cause severe, widespread human illness, it is highly likely that it has evolved to specifically thwart an effective immune response to infection.
Variola Virus. Variola is a human-specific virus. Generally it can be readily distinguished from other orthopoxviruses capable of infecting man (vaccinia, cowpox, monkeypox) by the characteristic small white pocks produced on the chorioallantoic membrane of developing 12-to 15-day-old chick embryos and the ceiling temperature of growth. How ...
28 maj 2024 · Variola virus is one of the oldest viruses known to infect and cause diseases in humans. Variola virus was the etiological agent of smallpox, an epidemic throughout the human history. The process of variolation began in the seventeenth century and was widely practiced.
8 sie 2023 · Smallpox is a member of the viral family poxvirus, genus orthopoxvirus, and species variola virus. Poxviruses are the largest of the human viral pathogens and have a brick-shaped appearance on electron microscopy. Variola virus measures approximately 300 nm to 350 nm long.
The variola virus is a large, brick-shaped, double-stranded DNA virus that serologically cross-reacts with other members of the poxvirus family, including ectromelia, cowpox, monkeypox,...
This is a transmission electron microscopic (TEM) image of a tissue section containing variola virus particles, the pathogen responsible for causing smallpox in humans. These organisms display an internal, dumbbell-shaped structure that represents the viral core containing the viral DNA.
