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Variola virus forms the characteristic pus-filled pustules and centrifugal rash dis-tribution in the infected patients while trans-mission occurs mainly through respiratory droplets during the early stage of infection. No antiviral drugs are approved for variola virus till date.
28 maj 2024 · Variola virus is one of the oldest viruses known to infect and cause diseases in humans. Variola virus was the etiological agent of smallpox, an epidemic throughout the human history. The process of variolation began in the seventeenth century and was widely practiced.
Variola Virus Research (ACVVR), which was established in 1999, oversees all research using live variola virus, based on the World Health Assembly decisions contained in WHA49.10, WHA52.10 and WHA 55.15.
10 paź 2024 · Structure of the Variola Virus. The Variola virus, a member of the Orthopoxvirus genus, exhibits a complex structure integral to its function and pathogenicity. Its large, brick-shaped virion is enveloped, measuring approximately 300 by 250 nanometers, making it one of the largest known viruses.
Infection of human cells grown in tissue culture could begin to provide answers to some of the following questions: Is there a unique molecule or series of molecules on the surface of human cells that makes them distinctly susceptible to infection with variola virus? What is the normal function of this molecule?
Variola Virus. Variola is a human-specific virus. Generally it can be readily distinguished from other orthopoxviruses capable of infecting man (vaccinia, cowpox, monkeypox) by the characteristic small white pocks produced on the chorioallantoic membrane of developing 12-to 15-day-old chick embryos and the ceiling temperature of growth. How ...
3 maj 2019 · Variola virus (VARV), the etiological agent of smallpox, is a historical cause of immense morbidity and mortality that resulted in an estimated 300–500 million deaths in the twentieth century alone.
