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Continuation of statin use in hospitalized patients with severe COVID-19 raises several concerns, mainly due to drug interactions (i.e. with macrolides) and transaminase elevations which are common in COVID-19 and are attributed either to the virus itself or to specific therapies i.e. remdesivir .
Cholesterol-lowering medications, mostly statins, are used by approximately one in four persons over the age of 40 in the U.S. [24] (with widespread use elsewhere), adding high importance to understanding potential interactions between statin use and COVID-19 infection.
When starting a patient on a statin in the era of COVID-19, patients may develop side effects from the statin that mimic the symptoms of COVID-19. Statins may lead to muscle-related symptoms, and muscle symptoms have been described with COVID-19.
In a recent meta-analysis of 4 observational studies, Kow and Hasan reported that statins were 30% effective in reducing the severity or mortality of COVID-19. 1–5 Since their report was published, 2 additional observational studies have appeared. 6,7 Most of these 6 studies reported on statin treatment in reducing 30-day mortality (Table 1).
14 lip 2022 · Statins could confer protective effects among COVID-19 patients by stabilizing and promoting regress of atherosclerotic plaques along with anti-inflammatory effects, inhibitor effects on...
16 cze 2021 · Inhibitors of 3-hydroxy-3methylgultaryl-coenzyme A reductase (statins) are one of the main groups of drugs used in preventing and treating cardiovascular diseases worldwide. They are widely available, cheap, and well-tolerated. Based on statins' pleiotropic properties, including improvement of endot …
15 lip 2021 · According to the research team, the use of statins or an anti-hypertension medication was associated with a 32 percent lower risk of death among COVID-19 inpatients with a history of...
