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1 lut 2024 · Claims that thiamine is effective for treatment of skin problems, chronic diarrhea, tiredness, mental problems, multiple sclerosis, nerve problems, and ulcerative colitis (a disease of the intestines), or as an insect repellant or to stimulate appetite have not been proven.
31 sty 2024 · Thiamine can be administered by enteral, intravenous (IV), or intramuscular (IM) routes. The oral route is indicated in patients who do not have IV access. The thiamine hydrochloride form is used to prevent and treat Wernicke encephalopathy.
Thiamine is a vitamin with antioxidant, erythropoietic, cognition-and mood-modulatory, antiatherosclerotic, putative ergogenic, and detoxification activities. Thiamine has been found to protect against lead-induced lipid peroxidation in rat liver and kidney. Thiamine deficiency results in selective neuronal death in animal models.
28 cze 2024 · Thiamine supplementation is an effective treatment for wet beriberi and can lead to significant improvement in clinical symptoms. However, our study did not reveal any significant improvement in cardiac function (LVEF) or heart size (LVEDV) even after adequate thiamine supplementation in CHF patients with prevalent TD.
7 lut 2018 · Thiamine is an essential cofactor for pyruvate dehydrogenase; it facilitates the conversion of pyruvate into acetyl-coenzyme A (CoA). In thiamine deficiency, pyruvate is shifted into anaerobic metabolism and converted into lactate. If lactic acid accumulates, lactic acidosis may develop.
12 lut 2013 · Thiamine should be administered via the parenteral (intravenous or intramuscular) route to achieve serum levels necessary to reverse the effects of deficiency, and to circumvent problems with absorption common in the medically ill.
13 wrz 2020 · Thiamine, also called vitamin B1 or aneurin, is a water-soluble vitamin, and it is an essential micronutrient for human beings [1]. It is essential both as a coenzyme and noncoenzyme, and is involved in many processes, particularly in energy transformation, and oxidative and nonoxidative carbohydrate metabolism.
