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22 lut 2023 · People with diabetes may have increased requirements for thiamine. Abstract. Background. Thiamine (vitamin B1) is an essential cofactor in glucose metabolism, but it remains unclear whether thiamine status is lower in individuals with diabetes compared to individuals with normal glucose metabolism. Aims.
A brief history of thiamine and diabetes. A research on PubMed using the MeSH terms “thiamine” AND “diabetes” permits to date back to 1947 the first official report of a link between this vitamin and diabetes: that paper described thiamine deficiency in diabetic as compared to healthy rats .
The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine deficiency in diabetic neuropathy became evident, and some pilot studies evaluated the putative effects of thiamine supplementation.
5 cze 2021 · The literature is more abundant about thiamine treatment of diabetic neuropathy. The symptoms of a neurological and cardiovascular disease, later identified as beriberi, had been described in traditional Chinese medicine as far as the third century AD [].In 1897, the Dutch physician Christiaan Eijkman, sent to the Dutch East Indies to study beriberi, first linked this disorder to a poor diet ...
The first reports of a link between thiamine and diabetes date back to the 1940s. Some years later, a role for thiamine defi-ciency in diabetic neuropathy became evident, and some pilot studies evaluated the putative efects of thiamine supplementa-tion.
12 maj 2011 · Thiamine is an essential cofactor in carbohydrate metabolism and individuals with diabetes are thiamine deficient. The pathophysiology of recognised complications of thiamine deficiency is similar to that underlying atherosclerosis and the metabolic syndrome, namely oxidative stress, inflammation and endothelial dysfunction.
5 cze 2021 · The first evidence of the beneficial effects of thiamine on microvascular cells involved in diabetic complications dates to 1996: from then on, several papers based on in vitro and animal...
