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23 godz. temu · Falling DNA synthesis costs, paired with expanding DNA assembly and delivery technologies and a powerful genome engineering toolbox, have driven the emergence of synthetic genomics, a field ...
4 sty 2022 · Here, we describe recent advances that address these limitations and point to a significant maturation of synthetic RNA-based devices. Synthetic RNA devices integrate sensing,...
17 sty 2022 · Synthetic DNA is the basis for promising technologies in data storage, barcoding, computing 62 and sercurity. In this review, the authors provide an overview of the field and its future.
Recent findings have revealed new roles and mechanisms for RNA beyond control of translation through the central dogma, including targeted RNA base editing and post-transcriptional modifications (part A ), circular RNA (circRNA) mechanisms (part B) and novel uses of RNA scaffolds (part C ).
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
2 lis 2021 · DNA encodes bioparts, bioparts are combined to make biological devices, and devices are built into biological systems. Synthetic biology is working towards a ‘plug-and-play’ concept, in which off-the-shelf bioparts will be able to be loaded and run in finely characterised chasses.
19 maj 2017 · However, the number of available devices is limited due to the difficulty in the detection of endogenous proteins within a cell. Here, we show a strategy to construct synthetic mRNA devices that detect endogenous proteins in living cells, control translation and distinguish cell types.
