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4 sty 2022 · Recent findings have revealed new roles and mechanisms for RNA beyond control of translation through the central dogma, including targeted RNA base editing and post-transcriptional...
Recent findings have revealed new roles and mechanisms for RNA beyond control of translation through the central dogma, including targeted RNA base editing and post-transcriptional modifications (part A ), circular RNA (circRNA) mechanisms (part B) and novel uses of RNA scaffolds (part C ).
19 lis 2018 · In this study, we construct a set of RNA-based logic circuits with RBPs that detect multiple miRNA inputs and regulate the output protein expression (Fig. 1a). We create five logic gates (AND,...
1 cze 2020 · Synthetic RNA molecules expressed within cells can be optimized for a variety of tasks that include control of gene expression and organization of small molecules and proteins. Here, we review recent research advances that exploit RNA structure for synthetic biology applications.
23 wrz 2019 · Synthetic RNA-based genetic devices dynamically control a wide range of gene-regulatory processes across diverse cell types. However, the limited throughput of quantitative assays in...
29 gru 2021 · Liu et al. review the development of the CRISPR-Cas toolbox and gene editing technologies, including the Cas nucleases used for gene editing as well as CRISPR-Cas-mediated DSB-dependent and DSB-independent gene editing tools, with an emphasis on precision tools and CRISPR-Cas-related technologies.
1 gru 2022 · This review summarizes our current understanding of RNA editing in various organisms especially focusing on C-to-U and U-to-C RNA editing in plants and pentatricopeptide repeat (PPR) proteins that are responsible for target RNA recognition and editing reactions.
