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16 mar 2012 · Here, we review recent advances in HIV-1 structural biology, focusing on the molecular mechanisms of viral replication and on the development of new therapeutics. Schematic overview of the...
29 sty 2021 · The capsid (CA) protein of the human immunodeficiency virus type 1 (HIV-1) is an essential structural component of a virion and facilitates many crucial life cycle steps through...
Abstract | Three-dimensional molecular structures can provide detailed information on biological mechanisms and, for cases in which the molecular function affects human health, can...
16 mar 2012 · Key Points. HIV-1 replication relies on the proper functioning of specific viral proteins, three of which — protease, integrase, and reverse transcriptase with associated RNase H activity —...
HIV-1 arose through several independent zoonotic transmissions of simian immunodeficiency viruses during the last century 1–3. Today, HIV-1, along with its less widespread cousin HIV-2, infects over 30 million people worldwide.
29 sty 2021 · The capsid (CA) protein of the human immunodeficiency virus type 1 (HIV-1) is an essential structural component of a virion and facilitates many crucial life cycle steps through interactions with host cell factors.
The Structural Biology of HIV. HIV (Human Immunodeficiency Virus) is composed of two strands of RNA, 15 types of viral proteins, and a few proteins from the last host cell it infected, all surrounded by a lipid bilayer membrane.
