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10 paź 2024 · Stargardt’s: The State of The Art in 2024. An in-depth review of the pathophysiology and diagnostic clues, as well as potential therapies on the horizon. Stargardt disease was first described by German ophthalmologist Karl Stargardt in 1909 and remains the most common juvenile macular dystrophy, with an incidence of ~1/10,000 individuals worldwide.
21 sie 2017 · STGD is generally not known to be associated with other ocular or systemic finding. There is, however, one exceptional report of STGD presenting in association with mental retardation, corpus callosum hypoplasia, or agenesis, as well as craniofacial dysmorphic features, including prominent ear lobules, flared eyebrows, and high-arched palate. 31
26 lip 2024 · Stargardt disease (STGD) is the most common form of inherited juvenile macular dystrophy and is caused by sequence variants in the ABCA4 gene. Due to its genetic complexity and phenotypic variability, STGD poses significant therapeutic challenges.
6 mar 2023 · To explore fundus autofluorescence (FAF) imaging as an alternative to electroretinography as a noninvasive, quick, and readily interpretable method to predict disease progression in Stargardt disease (STGD).
Stargardt disease macular dystrophy (STGD) is a common hereditary macular dystrophy, affecting approximately 1 in every 8000 to 10 000 individuals. Those with STGD typically begin to experience vision loss between 8 and 20 years of age.
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