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2 sty 2018 · The selective serotonin reuptake inhibitors (SSRIs) are the most extensively studied of the newer antidepressants and are increasingly being used as first-line treatment for depression (Anderson et al, 2000).
1 maj 2023 · Selective serotonin reuptake inhibitors (SSRIs) are a class of medications most commonly prescribed to treat depression. They are often used as first-line pharmacotherapy for depression and numerous other psychiatric disorders due to their safety, efficacy, and tolerability.
There have been inconsistent findings from randomised controlled trials (RCTs) and systematic reviews on the efficacies of selective serotonin reuptake inhibitors (SSRIs) as the first-line treatment of major depressive disorder (MDD).
5 maj 2007 · Compare Antidepressants: differences and similarities of Selective Serotonin Reuptake Inhibitors (SSRIs), comparison of effectiveness, side effects, drug interactions, pharmacokinetic and pharmacodynamic differences.
Procedure template. Purpose. The purpose of this guidance is to advise clinicians about strategies to swap or stop antidepressants in primary or secondary care. It is a guide only and does not replace clinical judgement or a thorough assessment of the individual circumstances.
All antidepressant switches must be carried out cautiously and under close observation. Conservative switching strategies involve gradually tapering the first antidepressant followed by an adequate washout period before the new antidepressant is started.
Consider SSRIs when depression, or anxiety disorder is moderate to severe, interferes with daily activities of living, participation in psychotherapy, or when patient has limited improvement despite engaging in psychotherapy.
