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Although the selective serotonin reuptake inhibi-tors (SSRIs) have better overall safety and toler-ability than older antidepressants, broad-based experience with SSRIs has shown the frequency and type of side effects to be increased relative to clinical trial data.
Sexual side effects are common with most antidepressants. Bupropion and mirtazapine may be least problematic. Many antidepressants are substrates of CYP450 enzymes. See our Cytochrome P450 Drug Interactions chart to help check for interactions. --absent or rare to ++++ relatively common.
SSRIs are slightly different in how quickly they work and how long they stay in the body. Their side effects also differ somewhat. Common side effects include nervousness, problems sleeping, headache, dry mouth, nausea, changes in sexual desire, and erectile dysfunction.
A specific treatment to reverse the effects of sertraline does not exist. What are the possible side effects of sertraline? Common side effects • Headache, nausea, diarrhea, dry mouth, increased sweating • Feeling nervous, restless, fatigued, sleepy or having trouble sleeping (insomnia)
The most common side effects of SSRIs are nausea, headaches, decreased sex drive, and feeling “jittery.” Some patients also have noticed fatigue and difficulty sleeping. Many side effects go away after taking the medication consistently for 1-2 weeks.
SSRI Side Effects and Management strategies If side effects occur, they are most notable during the initial 4 weeks of titrating the dose. Mild & Common Side effects (~10%) Management strategies GI upset (Nausea, diarrhea, pain) Take with food Usually subsides within 2 weeks Headache Supportive care
Side effects from SSRIs are usually mild and do not last long. Some people will not have any side effects. If you have minor side effects, try staying on the medicine for a few weeks. Minor side effects often go away after your body gets used to the new medicine.
