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To test the notion that SSRIs administered immediately before or after surgery were more likely to represent continuation of a home medication than initiation of antidepressant therapy during a hospitalization for surgery, we created 2 additional SSRI variables.
How soon after the operation can the SSRI be restarted will depend on the nature of the procedure and the course of recovery. The length of time off medication increases the risk of symptom recrudescence and relapse of MDD.
12 lut 2018 · We believe that the SSRI administration during hospitalization probably reflects chronic use, but we have no evidence to confirm this. Similarly, some patients may have been diagnosed with depression and started therapy months or years after surgery.
29 kwi 2013 · suggests that holding SSRIs for longer time periods after surgery (or potentially holding them longer preoperatively) may be worthy of investigation. While risks for mortality were...
24 cze 2013 · Receiving SSRIs in the perioperative period is associated with a higher risk for adverse events. Determining whether patient factors or SSRIs themselves are responsible for elevated risks requires prospective study.
Accumulating clinical evidence, supported by biological rationale, supports a statistically significant impact of SSRIs on the risk of bleeding. However the current data do not unequivocally support this to be of clinically importance in the preoperative period.
The updated guideline for preoperative evaluation of adults undergoing noncardiac surgery from the European Society of Anaes-thesiology and Intensive Care addresses the management of some of the psychotropic medications commonly encountered in the perioperative setting.3 However, to date, there are no guidelines available in the United States th...
