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3.1.1. Effect of Long-Term Artificial Sweetener Consumption on Lipid Profile. Our study found that the levels of TC, TG, LDL, and TC/HDL increased significantly, whereas the level of HDL decreased in diabetic patients long-term sweetener consumers (DS) relative to the group healthy (H).
27 lis 2017 · This leads to chronic hyperglycaemia (i.e. elevated plasma glucose levels) and disturbances of carbohydrate, fat, and protein metabolism. In the long term, this condition leads to complications such as retinopathy, nephropathy, neuropathy, and an increased risk for cardiovascular diseases.
3 kwi 2023 · The results suggest that saccharin and cyclamate increased HbA1C (+11.16%), MDA (+52.38%), TG (+16.74%), LDL (+13.39%), and TC/HDL (+13.11%) in healthy volunteers. Diabetic patients consuming sweeteners showed increased FSG (+17.51%), ceruloplasmin (+13.17%), and MDA (+8.92%).
Sodium cyclamate was tested for carcinogenicity both alone and in combination with other chemicals in different animal species and by several routes of administration. Following its oral administration to two strains of mice, an increased incidence of lymphosarcomas was observed in female mice of one strain; a few bladder tumours were seen in ...
Sodium cyclamate is a potent sweetening agent. It has been subjected to numerous safety and carcinogenicity studies. Animal data led to warning against excessive and indiscriminate use a long time ago, causing the World Health Organization in 1967 to adopt a safety limit of 50 mg/kg.
The results of these studies have been inconsistent. For example, intake of artificially sweetened beverages was associated with an increased risk of kidney cancer in a US cohort of postmenopausal women but not in a European cohort of healthy adults .
2 lis 2021 · Request PDF | On Nov 2, 2021, Husni Hasan and others published Impact of long term cyclamate and saccharin consumption on biochemical parameters in healthy individuals and type 2 diabetes...