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Sodium cyclamate is a potent sweetening agent. It has been subjected to numerous safety and carcinogenicity studies. Animal data led to warning against excessive and indiscriminate use a long time ago, causing the World Health Organization in 1967 to adopt a safety limit of 50 mg/kg.
In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Cyclamates. Sodium cyclamate is a potent sweetening agent. It has been subjected to numerous safety and carcinogenicity studies.
27 lis 2017 · This leads to chronic hyperglycaemia (i.e. elevated plasma glucose levels) and disturbances of carbohydrate, fat, and protein metabolism. In the long term, this condition leads to complications such as retinopathy, nephropathy, neuropathy, and an increased risk for cardiovascular diseases.
However, the global market for artificial sweeteners has decreased considerably over the past 10 years due to their possible harmful effects on human health, for example, cancer (Weihrauch and Diehl, 2004), obesity (Yang, 2010), and diabetes (Brown et al., 2010).
Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
Several low-calorie synthetic sweeteners have recently emerged in the pharmaceutical and food industries, but their health risks due to their side effects restrict their adoption [4,5]. Several previous studies have shown that the use of artificial sweeteners can be hazardous to human health [6,7].
18 maj 2024 · Symptoms of Low Sodium Levels. While people with mild hyponatremia often have no symptoms, the likelihood of them occurring increases the more that sodium levels drop. Common signs and symptoms of low sodium include: Headaches, dizziness, and/or loss of balance. Fatigue, drowsiness, mental confusion, or trouble concentrating.
