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27 lis 2017 · This leads to chronic hyperglycaemia (i.e. elevated plasma glucose levels) and disturbances of carbohydrate, fat, and protein metabolism. In the long term, this condition leads to complications such as retinopathy, nephropathy, neuropathy, and an increased risk for cardiovascular diseases.
Several low-calorie synthetic sweeteners have recently emerged in the pharmaceutical and food industries, but their health risks due to their side effects restrict their adoption [4,5]. Several previous studies have shown that the use of artificial sweeteners can be hazardous to human health [6,7].
In Meyler's Side Effects of Drugs (Sixteenth Edition), 2016. Cyclamates. Sodium cyclamate is a potent sweetening agent. It has been subjected to numerous safety and carcinogenicity studies.
Concerns about artificial sweeteners and cancer initially arose when early studies linked the combination of cyclamate plus saccharin (and, to a lesser extent, cyclamate alone) with the development of bladder cancer in laboratory animals, particularly male rats.
Cyclamate is an artificial sweetener (code E952) with a high sweetening power; according to numerous studies, in some people it can lead to the formation of a substance (CHA) which, when given in significant doses in animal testing, resulted in testicular damage.
However, the global market for artificial sweeteners has decreased considerably over the past 10 years due to their possible harmful effects on human health, for example, cancer (Weihrauch and Diehl, 2004), obesity (Yang, 2010), and diabetes (Brown et al., 2010).
Contents. < Prev Next > CYCLAMATES (Group 3) Go to: A. Evidence for carcinogenicity to humans ( inadequate) The evidence that the risk of cancer is increased among users of artificial sweeteners is inconsistent 1.
