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30 lip 2021 · Natural killer (NK) cells participate in cancer immunosurveillance and cancer immunotherapy. Live cell imaging of cancer cells targeted by NK cells, published today in BMC Biology by Zhu et al., reveals a remarkable diversity of programmed cell death pathways induced in individual cells.
- Rac1/ROCK-driven Membrane Dynamics Promote Natural Killer Cell Cytotoxicity Via Granzyme-Induced Necroptosis
Natural killer (NK) cells detect and kill virus-infected...
- Rac1/ROCK-driven Membrane Dynamics Promote Natural Killer Cell Cytotoxicity Via Granzyme-Induced Necroptosis
The cytotoxic effect was also observed in cancer cells. Sodium benzoate has also been shown to induce apoptosis and affect NFκB in these cells . It should be emphasized that this compound inhibited colon cancer cell proliferation much more strongly than fibroblast cell proliferation. 3.2. Sodium Benzoate in Major Depressive Disorder and Anxiety
22 mar 2018 · Inhibition of NFκB activity further increased Bim levels. Overall, these results suggest that NaB induces apoptosis and activates NFκB in HCT116 colon cancer cells. Activation of NFκB emerges as target in an attempt to protect cells against apoptosis.
1 paź 2024 · Furthermore, sodium benzoate has been inspected for its potential ability to generate benzene, a known cause of cancer, when mixed with ascorbic acid (vitamin C) under certain circumstances [32]. Regulatory organizations have established stringent regulations to mitigate this risk, guaranteeing that the levels of benzene in food and drinks ...
24 cze 2011 · We found that SB induced cell death in a dose-dependent manner. Even 0.1% (w/v) SB, a concentration typically added to soft drinks, produced a significant decrease in cell viability in rat cortical and HeLa cells.
2 lip 2022 · These findings suggest that intratumoral lactic acidosis could effectively protect cancer cells against starvation and glucose deprivation.
25 cze 2024 · Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells — which kill infected, damaged, or malignant cells in the body — more effective against cancer. The approach, they say, could enable new treatments for solid tumors in the future.