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  1. Mandatory smallpox vaccination came into effect in Britain and parts of the United States of America in the 1840s and 1850s, as well as in other parts of the world, leading to the establishment of the smallpox vaccination certificates required for travel.

  2. The World Health Organization (WHO) declares smallpox eliminated worldwide due to vaccinations. Smallpox vaccination ends. Before the smallpox vaccine, smallpox had been considered one of the deadliest infectious diseases. About 300 million people died of smallpox in the 20th century.

  3. Smallpox vaccine was successfully maintained in cattle starting in the 1840s, and calf lymph vaccine became the leading smallpox vaccine in the 1880s. First-generation vaccines grown on the skin of live animals were widely distributed in the 1950s–1970s to eradicate smallpox.

  4. 24 paź 2024 · Smallpox vaccine was introduced by British physician Edward Jenner, who in 1796 used the cowpox virus (vaccinia) to confer protection against smallpox in humans. Prior to that use, however, the principle of vaccination had been applied by Asian physicians who gave children dried crusts from the lesions of people suffering from smallpox to ...

  5. The global eradication of smallpox was a tremendous achievement made possible by the development of an effective vaccine. Routine vaccination of the general population is no longer recommended. However, stocks of variola virus, the causative agent ...

  6. 3 sty 2014 · The smallpox vaccine, introduced by Edward Jenner in 1796, was the first successful vaccine to be developed. He observed that milkmaids who previously had caught cowpox did not catch smallpox and showed that inoculated vaccinia protected against inoculated variola virus.

  7. For over 2 centuries, people have been vaccinated against deadly diseases, ever since the world’s first vaccine was devised against smallpox. History has taught us that a full and effective global response to vaccine-preventable diseases takes time, financial support and collaboration – and requires continued vigilance.

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