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31 lip 2023 · Our findings show a strikingly high contribution of sickle cell disease to all-cause mortality that is not apparent when each death is assigned to only a single cause. Sickle cell disease mortality burden is highest in children, especially in countries with the greatest under-5 mortality rates.
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The four steps are highlighted: (1) sickle cell...
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GBD 2021 Sickle Cell Disease Collaborators. Global,...
- Time to Act on The Most Neglected Global Health Problem
Despite being the first monogenic disease described in...
- Sorafenib Maintenance After Allogeneic Haemopoietic Stem-Cell Transplantation in Patients With Flt3-Itd Acute Myeloid Leukaemia
With extended follow-up, sorafenib maintenance after...
- Global Advocacy From Zambia for The Hopes and Dreams of People With Sickle Cell Disease
My name is Lwimba Kasongo and I am a sickle cell disease...
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Chętnie wyświetlilibyśmy opis, ale witryna, którą oglądasz,...
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8 mar 2019 · The prognosis for people with sickle cell anemia has improved over the last few decades, but it can still have an effect on life expectancy. We’ll go over survival rates, average life...
15 maj 2024 · Key points. Sickle cell disease (SCD) affects about 100,000 people in the United States; more than 90% are non-Hispanic Black or African American, and an estimated 3%–9% are Hispanic or Latino. The estimated life expectancy of those with SCD in the United States is more than 20 years shorter than the average expected.
8 wrz 2016 · Median survival in patients with high hospital admission rates (>0.5 admissions per year) was 60 years (CI, 43-77 years), significantly lower than that in patients with low admission rates (≤0.5 per year) (P = .001; Figure 1B).
15 cze 2023 · Total SCD mortality ranks 12th in all leading causes of death in children younger than 5 years globally, 28-places higher than cause-specific SCD mortality, demonstrating the enormous and under-appreciated burden of the disease.
Among sickle cell genotypes, survival curves demonstrated that HbSS and Sβ 0 portended the worst prognoses, followed by Hb SC and Sβ + (Figure 1A). Overall median survival for HbSS and Sβ 0 was 58 years and for Hb SC and Sβ + was 66 years, a difference that was statistically significant (p=0.0031).
18 lip 2024 · INTRODUCTION. Vaso-occlusive phenomena and hemolysis are the clinical hallmarks of sickle cell disease (SCD). Vaso-occlusion results in recurrent painful episodes (previously called sickle cell crisis) and a variety of serious organ system complications that can lead to life-long disabilities and even death.
