Search results
How to use the Seretide Diskus inhaler or other brands using the same Diskus device. This type of inhaler is used in asthma and COPD and is very common. http...
GROUP 14A: SERETIDE (Salmeterol + Fluticasone)
How to use Seretide Diskus or similar inhalers. A demonstration of the inhaler technique. You would need to turn the disk completely open, by pulling at the notch on one side. This will expose a...
Mechanism of action. Beta-2 adrenoceptor stimulation causes relaxation of bronchial smooth muscle, bronchodilation, and increased airflow. 1
Its mechanism of action can be explained by binding to a specific exo-site domain of the beta 2-receptor protein to produce continuous stimulation of the active site of the receptor, which gives salmeterol a profile of pharmacological activity unlike that of other beta 2-agonists.
Mechanism of action and pharmacodynamic effects: Seretide contains salmeterol and fluticasone propionate which have differing modes of action. The respective mechanisms of action of both drugs are discussed below. Salmeterol:
Clinical trials are underway to examine the potential role of Seretide in patients with chronic obstructive pulmonary disease (COPD). Salmeterol has been shown to be an effective first-line bronchodilator in COPD and fluticasone has been shown to reduce the frequency and or severity of exacerbations in COPD patients in two key trials.
