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  1. 4 lut 2022 · There is an urgent need for controlled studies to guide the management of CC. Treating RP, keeping hands warm, and avoiding trauma are important preventative measures. Small retrospective, prospective, and case studies have reported varied success with diverse treatments for CC in SSc, which are described below in brief .

  2. 25 cze 2024 · Part 1 of this consensus provides clinicians with an overview of the diagnosis and treatment of localized scleroderma (morphea), and systemic sclerosis including overlap syndromes. Part 2 of this consensus provides an additional overview of the diagnosis and treatment of scleromyxoedema and scleroedema (of Buschke).

  3. 3 lut 2022 · Systemic sclerosis (SSc), also referred to as systemic scleroderma or scleroderma, is a rare, complex immune-mediated connective tissue disease characterized by progressive skin fibrosis and other clinically heterogenous features.

  4. The most common initial symptoms and signs are vascular, such as Raynaud's phenomenon, which is often long-lasting, as well as insidious swelling of the distal extremities, followed by gradual thickening of the skin of the face and fingers with eventual skin ulceration.1 The pathophysiology of SSc involves endothelial and vascular damage and ...

  5. Part 1 of this guideline provides clinicians with an overview of the diagnosis and treatment of localized scleroderma (morphea), and systemic sclerosis including overlap syndromes of systemic sclerosis with diseases of the rheumatological spectrum.

  6. Here, we comprehensively discuss current treatment options for scleroderma, encompassing old, new, and future potential treatment options. In addition, we summarize data from new clinical trials that have the potential to modify the disease process and improve long-term outcomes in SSc.

  7. 8 sie 2017 · The clinical symptoms of scleredema include cutaneous and extracutaneous findings, the latter being present especially in types 2 and 3 scleredema. 45, 70, 73-81 In the early stages, scleredema manifests as a woody, non-pitting, indurated plaques of the skin of the neck, which later spreads to shoulders and the upper part of the trunk, but ...

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