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  1. 15 cze 2024 · Treatment. There is no treatment that can cure or stop the overproduction of collagen that happens in scleroderma. But a variety of treatments can help control symptoms and prevent complications.

  2. 15 cze 2024 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.

  3. 1 kwi 2020 · The Scleroderma Clinic specializes in providing comprehensive care for people with scleroderma and related conditions. Scleroderma, also called systemic sclerosis, is a complex autoimmune disease that can affect many organ systems besides the skin.

  4. Scleroderma is a multisystem disease with variable expression; thus, any treatment plan must be holistic, yet at the same time focus on the dominant organ disease. The goal of therapy is to improve quality of life by minimizing specific organ involvement and subsequent life-threatening disease.

  5. Therapy should be directed at the underlying cause. For lower gastrointestinal tract symptoms, a bowel regimen (eg, polyethylene glycol) for constipation and a trial of antibiotics for diarrhea may improve quality of life, and IBS medications may be helpful.

  6. Juvenile localized scleroderma (morphea) is the predominant scleroderma in childhood which affects the skin and may extend to the underlying fascia, muscle, joints and bone. The assessment of activity and damage can be done with a validated instrument like LoSCAT.

  7. Mortality is extremely rare in juvenile LS, but morbidity is common, with patients at risk for severe disfigurement and functional impairment. Scleroderma treatment is directed towards controlling inflammation and managing specific problems. Early diagnosis can greatly improve outcome.

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