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18 gru 2023 · Scleroderma is a condition that causes a distinctive change in the skin. The skin produces too much collagen, which causes tight, shiny skin. The skin can become so tight that it makes it difficult to move the joints.
8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.
Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.
9 sty 2023 · Scleroderma is characterized by progressive skin and connective tissue tightening and hardening. It may also affect subcutaneous tissue, muscles, and internal organs. There are five stages of scleroderma symptom development and progression.
Anyone can develop scleroderma, but some groups of people have a higher risk: People assigned female at birth (AFAB) are four times more likely than people assigned male at birth (AMAB) to develop scleroderma. People 30 – 50 years old — it’s rare for people younger than 30 to have scleroderma.
21 mar 2024 · Scleroderma symptoms can include hardening of the skin, joint and muscle pain, digestive issues, swollen hands, and narrowing of blood vessels. Learn about the different types and view pictures to help identify some common symptoms.