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  1. 18 gru 2023 · Scleroderma is an autoimmune condition in which the body produces too much collagen. This affects the skin by causing it to be tight and shiny and can also affect internal organs, causing significant organ dysfunction. Most often, scleroderma is seen on the arms, legs, and face but can occur anywhere.

  2. 8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.

  3. 3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.

  4. scleroderma.org › wp-content › uploadsScleroderma Facts

    • It’s estimated that there are 300,000 cases of scleroderma in the United States. • Women make up 80 percent of scleroderma cases, but men, young children and teens also get scleroderma. • Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and

  5. 27 lis 2021 · Fact Sheet. Scleroderma Overview and Causes. Introduction. Scleroderma is an autoimmune disease which means that it is a condition in which the body’s immune system attacks its own tissues. The normal role of the immune system is to provide protection from outside invaders such as bacteria and viruses.

  6. Some types of scleroderma affect the skin and internal organs like the lungs and kidneys. The following symptoms can be a warning sign that scleroderma is affecting an internal organ: Digestive system. Problems swallowing. Heartburn. Diarrhea. Constipation. Bloated feeling after eating. Weight loss without trying. Other organs. High blood ...

  7. 4 kwi 2022 · Key points. Systemic sclerosis (SSc): autoimmune disorder of connective tissue; characterised by increased fibrosis and vascular changes; affects skin and internal organs. Types: Limited cutaneous SSc (lcSSc): skin involvement below elbows and knees, face; less internal organ involvement.

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