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18 gru 2023 · Scleroderma is an autoimmune condition in which the body produces too much collagen. This affects the skin by causing it to be tight and shiny and can also affect internal organs, causing significant organ dysfunction. Most often, scleroderma is seen on the arms, legs, and face but can occur anywhere.
Although patients who develop scleroderma (SSc) later in life (≥ 65 years) may express the entire clinical spectrum of disease, we hypothesize that patients with late-age onset incur a different risk for specific organ manifestations of disease compared to those with younger-age onset SSc.
8 lut 2023 · Scleroderma commonly affects people 30 to 50 years of age but is found in all ages. Also, women are typically more likely than men to receive a diagnosis of this condition.
3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.
9 sty 2023 · Scleroderma is characterized by progressive skin and connective tissue tightening and hardening. It may also affect subcutaneous tissue, muscles, and internal organs. There are five stages of scleroderma symptom development and progression. Stage 1: Immune system malfunction
• It’s estimated that there are 300,000 cases of scleroderma in the United States. • Women make up 80 percent of scleroderma cases, but men, young children and teens also get scleroderma. • Scleroderma typically strikes between the ages of 25 and 55. • In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and
Anyone can develop scleroderma, but some groups of people have a higher risk: People assigned female at birth (AFAB) are four times more likely than people assigned male at birth (AMAB) to develop scleroderma. People 30 – 50 years old — it’s rare for people younger than 30 to have scleroderma.
