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Overall, 2084 (91%) patients developed SSc prior to age 65; whereas 216 (9%) were ≥65 years. Late-age onset patients had a significantly higher proportion of anti-centromere antibodies (42% vs 27%; p=0.001) compared to younger-age onset.
Scleroderma typically strikes between the ages of 25 and 55. In 95 percent of cases, scleroderma begins with Raynaud Phenomenon (hands and feet abnormally sensitive to cold). Federal funding for scleroderma research lags behind funding for other diseases of similar prevalence.
1 sty 2011 · The age of scleroderma onset can impact the course of disease and increase the risk for organ-specific complications such as pulmonary vascular disease. As individuals age with scleroderma, physicians should focus on careful monitoring of each organ system and comprehensive medical care.
9 sty 2023 · The five-year survival rate (that is, patients who are still alive 5 years following diagnosis) among patients with diffuse cutaneous systemic sclerosis is about 84%. Five-year survival among patients with limited skin (cutaneous) systemic sclerosis is high — over 90%.
3 lut 2022 · The annual incidence of SSc is estimated to be between 0.6 and 5.6 per 100,000 adults and prevalence between 7.2 and 44.3 per 100,000 adults. 1-5 Women are affected between 3.8 and 15 times more frequently than men. 1 The mean age at diagnosis is 33.5 to 59.8 years. 1 Pediatric SSc represents less than 5% of all cases.
1 mar 2021 · This review aims to provide an overview and summary of the recent epidemiological studies in systemic sclerosis. Recent findings: Global trends of scleroderma demonstrate greater prevalence of SSc in European, North, and South American patients compared with East Asian patients.
• Scleroderma Overview –This initial section gives a general description of the scleroderma family of diseases and discusses the affected population, possible causes, and typical symptoms. • Scleroderma Diagnosis – Diagnosing someone with scleroderma can be a lengthy
