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17 wrz 2024 · New bone formation surpasses the resorptive action of osteoclasts, which release calcium and phosphorus from bones, resulting in a net upsurge in bone density and strength. The mechanism outlined above renders it a very effective therapy for osteoporosis (Föger-Samwald et al., 2020).
18 lip 2023 · For patients with osteoporosis, the long-term use of bone-specific pharmacological therapies, including antiresorptive and/or osteoanabolic approaches, has raised concerns around adverse...
23 lip 2024 · This comprehensive review aims to provide clinicians and researchers with a mechanistic understanding of osteoporosis pathogenesis and the therapeutic mechanisms of existing medications. By elucidating these insights, this review seeks to inform evidence-based decision-making and optimize therapeutic outcomes for patients with osteoporosis.
3 Department of Premedical Sciences, College of Medicine, Chosun University, ... Due to its adverse effects, strontium ranelate is considered a second-line therapy, and is administered when other osteoporosis therapies cannot be used or are ineffective (78,101). Common adverse effects include cardiovascular disorders, venous thromboembolism ...
7 lis 2017 · Treatment of osteoporosis is strictly related to severity of pathology and consists on prevention of fragility fractures with a correct lifestyle and adequate nutritional supplements, and use of pharmacological therapy, started in patients with osteopenia and history of fragility fracture of the hip or spine.
4 wrz 2022 · Recently, cytokine immunotherapy, gene therapy, and stem cell therapy have become new approaches for the treatment of various diseases. This article reviews the latest research on bone remodeling mechanisms, as well as how this underpins current and potential novel treatments for osteoporosis.
11 sie 2024 · Prevention of osteoporosis can be achieved by consuming the nutrients needed for bone health, vitamin D and calcium from food, which can be the first choice for the prevention and treatment of osteoporosis (Weaver et al., 2016; Paschalis et al., 2017), while anti-osteoporosis drug therapy is necessary to improve bone mass and reduce the risk of ...
