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Most patients with sarcoidosis present one of the following: intrathoracic lymphadenopathy, pulmonary involvement, cutaneous symptoms or eye impairment. Skin manifestations include macules, papules, simple or multiple plaques, which can commonly affect the face, posterior neck, torso and extremities.
21 lut 2019 · Once the diagnosis is established, a systematic evaluation for the extent of disease should be conducted. This should, at minimum, include history, physical examination, measurement of calcium, liver enzyme, and creatinine levels, urinalysis, ECG, and ophthalmologic examination.
29 kwi 2024 · An overview of the typical clinical manifestations and diagnosis of sarcoidosis is presented here. Organ-specific clinical manifestations involving the heart, neurologic system, gastrointestinal tract, skin, bone, joint, and other extrapulmonary tissues are discussed in more detail separately.
30 sty 2019 · Sarcoidosis can be difficult to diagnose because the disease often produces few signs and symptoms in its early stages. When symptoms do occur, they may mimic those of other disorders. Your doctor will likely start with a physical exam and discuss your symptoms.
30 sty 2019 · Sarcoidosis is a disease characterized by the growth of tiny collections of inflammatory cells (granulomas) in any part of your body — most commonly the lungs and lymph nodes. But it can also affect the eyes, skin, heart and other organs.
2 kwi 2019 · Mean serum creatinine level at presentation was 3.6 ± 1.2 mg/dL, eGFR was 19 ± 7 mL/min and mean creatinine clearance 26 ± 16 mL/min . Hypercalcemia was present in 5 of 7 patients at presentation (mean 5.9 ± 0.4 mval/L, range 5.4–6.3 mval/L).
For patients with sarcoidosis who have neither renal symptoms nor established renal sarcoidosis, we suggest baseline serum creatinine testing to screen for renal sarcoidosis (conditional recommendation, very low-quality evidence).
