Search results
8 sie 2023 · Rubella, or German measles, is a mild viral infection that typically occurs in children and non-immune young adults. It typically begins with low-grade fever, malaise, and lymphadenopathy, followed by a brief generalized erythematous maculopapular rash.
Structure. Rubella virus is a spherical, 40- to 80-nm, positive-sense, single-stranded RNA virus with spike-like, hemagglutinin-containing surface projections. An electron-dense 30 to 35 nm core is surrounded by a lipoprotein envelope.
26 kwi 2021 · This review focuses on the life cycle of RUBV with emphasis on recent findings on the structures of the virus particle and its component proteins and on the mechanisms of virus entry, fusion, assembly, and budding.
logical, biochemical, and structural studies, providing a platform to begin understanding the life cycle of RUBV at the molecular level. This review concentrates on recent work on RUBV, focusing on the virion; its structural components; and its entry, fusion, and as-sembly mechanisms.
Rubella virus was fi rst isolated from cell culture in 1962,1 and contains a single-stranded, positive-sense RNA genome.2 The virus belongs to the Togaviridae family and is the sole member of the Rubivirus genus. Rubella virus is the causative agent of rubella disease or so-called German measles.
Rubella virus has two envelope glycoproteins, E1 and E2 (481 and 282 amino acids long, respectively), which are anchored in the viral membrane by a carboxy-terminal transmembrane segment.
Rubella is an acute illness caused by rubella virus and characterised by fever and rash. Although rubella is a clinically mild illness, primary rubella virus infection in early pregnancy can result in congenital rubella syndrome, which has serious medical and public health consequences.
