Search results
Rubella virus contains three major structural polypeptides: two membrane glycoproteins, E1 and E2 and a single nonglycosylated RNA-associated capsid protein, C, within the virion. One of the envelope proteins, E1, is responsible for viral hemagglutination and neutralization.
8 sie 2023 · Rubella virus encodes two non-structural proteins (p90 and p150) and three structural proteins; glycoprotein (E1 and E2) and the capsid protein (CP). The E1 protein is responsible for receptor-mediated endocytosis and induces the immune response through hemagglutination-neutralizing epitopes.
26 kwi 2021 · This review focuses on the life cycle of RUBV with emphasis on recent findings on the structures of the virus particle and its component proteins and on the mechanisms of virus entry, fusion, assembly, and budding.
26 kwi 2021 · This review concentrates on recent work on RUBV, focusing on the virion, its structural components, and its entry, fusion, and assembly mechanisms. Important features of RUBV are compared with those of viruses from other families.
Epidemiology, Prevention, Control, Treatment. Rubella virus is shed in oropharyngeal secretions and is presumed to be spread by the respiratory route. It is highly transmissible, usually being acquired by school-age children, and spreads readily within the family.
Rubella virus contains three major structural proteins, E1, E2, and C. E1 and E2 are glycosylated envelope proteins that make up the spiked 5- to 6-nm surface projections of the viral surface. Monoclonal antibodies directed against epitopes of both E1 and E2 have neutralizing activity.
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy.
