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  1. 22 kwi 2024 · Initiate treatment with ROXICODONE in a dosing range of 5 to 15 mg every 4 to 6 hours as needed for pain, and at the lowest dose necessary to achieve adequate analgesia. Titrate the dose based upon the individual patient’s response to their initial dose of ROXICODONE.

  2. Calculates total daily morphine milligram equivalents. There is no completely safe opioid dose, and this calculator does not substitute for clinical judgment. Use caution when prescribing opioids at any dosage, and prescribe the lowest effective dose.

  3. Converts between different types and routes of opiates. This calculator is for double-checking opiate conversion, and should NOT be used as the primary means for ordering. Select the opiate and route that you wish to convert from. Input the total daily dose in milligrams of the opiate you are converting from.

  4. In order to calculate an oral Morphine Equivalent Daily Dose (oMEDD), multiply the current daily opioid dose by the conversion factor in column 3. For example, oMEDD of oxycodone 40mg/day = 40 x 1.5 = 60mg/day

  5. 6 sie 2024 · Detailed dosage guidelines and administration information for Roxicodone Solution (oxycodone hydrochloride). Includes dose adjustments, warnings and precautions.

  6. Consider the need to adjust dose for conditions that increase opiate risk (eg elderly, co-morbidities, renal or hepatic impairment). Where dose equivalence is expressed as a range, use the value that produces the lowest equivalent dose and titrate as necessary.

  7. Use the oral to parenteral equianalgesic ratio: 25 mg PO morphine = 10 mg IV Morphine or a 2.5:1 ratio. Some experts recommend starting the new opioid at roughly 75% of the calculated dose to account for inter-individual variation in first pass clearance and safety.

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