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4 wrz 2019 · The A, U, G, and C nucleobases in modern RNA all participate in secondary structure formation and replication. However, the rapid deamination of C to U and the absence of C in meteorite samples suggest that prebiotic RNA may have been deficient in cytosine.
A statistical reference for RNA secondary structures with minimum free energies is computed by folding large ensembles of random RNA sequences. Four nucleotide alphabets are used: two binary alphabets, AU and GC, the biophysical AUGC and the synthetic GCXK alphabet.
Hydroxyl radical footprinting data show that five sites in the 3' UTR of alfalfa mosaic virus RNA 4 are protected by coat protein, and four of the five protected regions contain AUGC or UUGC. Electrophoretic mobility band shift results suggest four coat protein binding sites in the 3' UTR.
18 wrz 2022 · TRANSCRIPTION: Transcription is the process of creating an mRNA strand or quite simple an RNA copy of DNA where the base pairs are (AUGC) and RNA polymerase is used to catalyze the formation of the nucleic acid based polymer.
12 gru 2004 · The crystal structure of an alfalfa mosaic virus RNA-peptide complex reveals that conserved AUGC repeats and Pro-Thr-x-Arg-Ser-x-x-Tyr coat protein amino acids cofold upon interacting. Alternating AUGC residues have opposite orientation, and they base pair in different adjacent duplexes.
9 sty 2023 · RNAsmc is driven by structural characteristics, which significantly aid in classification of RNA families, functional annotations, and analysis of allosteric effects after single-nucleotide changes in RNA transcripts.
26 cze 2024 · In this Review, we discuss recent technical advances in the determination of RNA structures, and the roles of RNA structures in RNA biogenesis and functions, including in transcription,...
