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1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
Human epidermal rete ridges. Sections of foetal (A–F) and whole mounts of adult (G and H) dorsal skin stained with (A and D) haemotoxylin and eosin or (B, C, E–H) antibodies to b 1 (red) and a...
The epidermis forms an undulating appearance, with intermittent regular protrusions of the epidermis layer (rete ridges or pegs) into the upper layers of the underlying dermis. In some areas of the body such as the palms and soles, the rete pegs are less pronounced.
1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
Download scientific diagram | Patterning human skin models with rete ridge-like structures. (A) Schematic illustration of the stamping, cell seeding, and longitudinal culture method.
Rete ridges surround the dermal papillae, which can be seen as small extensions protruding from the papillary dermis within the epidermis. These two structures are perfectly embedded; the alternation of a rete ridge with a dermal papilla creates a characteristic repetitive and wave-shaped pattern.
Download PDF. More. During human skin development, specific interactions between epidermal and dermal cell lineages give rise to fully functional skin that contains specialized appendages, including hair follicles, sweat glands, and rete ridges.