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1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
6 dni temu · Because rete ridges increase delamination energy, loss of this anatomical skin feature leads to higher injury susceptibility. Thus, our study suggests the ability of using mechanical cues to affect rete ridge formation in patients or in skin tissue engineering.
26 kwi 2022 · Melanocytes of the human skin epidermis are highly resistant to cell-death by apoptosis, contrasting with melanogenically-active melanocytes in the hair follicle (FMU). There appear to be some protective mechanisms in the hair follicle that limit genomic instability and melanomagenesis.
1 sty 2023 · Rete ridges (RRs) are distinct undulating microstructures at the junction of the dermis and epidermis in the skin of humans and certain animals. This structure is essential for enhancing the mechanical characteristics of skin and preserving homeostasis.
25 sie 2020 · How stem cells give rise to epidermis is unclear despite the crucial role the epidermis plays in barrier and appendage formation.
25 lis 2015 · Introduction. Skin is a large, complex organ that is constantly renewed throughout life. The interfollicular epidermis is arranged in a spatial hierarchy with cells becoming more differentiated as they move to the outer layers and eventually shed. Differentiating cells are replenished by a basal layer of proliferating keratinocytes.
Rete ridges surround the dermal papillae, which can be seen as small extensions protruding from the papillary dermis within the epidermis. These two structures are perfectly embedded; the alternation of a rete ridge with a dermal papilla creates a characteristic repetitive and wave-shaped pattern.
