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7 paź 2021 · Our study provided a comprehensive and quantitative index for assessing the prognosis for ALS patients, and the identified non-intervenable or intervenable factors will facilitate the development of treatment strategies for ALS.
Respiratory function plays a critical role in the prognosis and quality of life for patients with ALS. Slow vital capacity (SVC) has emerged as a key indicator of respiratory decline, with studies showing an average decrease of 2.73 to 2.90 percentage points per month in ALS patients [8].
We present a straightforward graphical method of predicting a patient's survival time from ALS diagnosis, taking into account the known prognostic factors of onset site, age at symptom onset, diagnostic delay, riluzole use, NIV use and respiratory muscle involvement.
28 kwi 2022 · Detecting ALS in elderly patients sooner could noticeably impact a person with ALS and their quality of life. Additionally, starting treatment at the early stages could slow down the disease progression and increase life expectancy for the individual.
7 lip 2018 · Noninvasive ventilation (NIV) has become the standard of care for respiratory support in patients with ALS. NIV use has demonstrated survival benefit and improved quality of life vs standard of care.
The median survival time from onset to death ranges from 20 to 48 months, but 10–20% of ALS patients have a survival longer than 10 years. Older age and bulbar onset are consistently reported to have a worse outcome. There are conflicting data on gender, diagnostic delay and El Escorial criteria.
ALS life expectancy is influenced by factors such as age at onset, site of onset, respiratory function, and nutritional status. Multidisciplinary care approaches have been shown to improve survival rates and quality of life for ALS patients.
