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Up to 95% of patients with ALS in the United States choose not to undergo tracheostomy; management of respiratory failure is therefore aimed at both prolonging survival as well as improving quality of life.
23 mar 2018 · Respiratory failure associated with declining muscle strength is the primary cause of death in ALS patients and typically occurs within 3–5 years (1). Moreover, approximately 3–5% of ALS patients present with respiratory failure (2, 3).
19 sty 2023 · A comprehensive, multidisciplinary approach to ALS respiratory care may minimize hospitalizations for acute respiratory failure, reduce need for emergent tracheostomy, improve patient-reported outcome measures, and facilitate developing clinical research initiatives.
22 lut 2022 · Respiratory dysfunction is a common cause of morbidity and mortality in many neuromuscular disorders, but particularly important in motor neuron diseases (MND), such as amyotrophic lateral sclerosis (ALS) or spinal muscular atrophy (SMA).
1 lut 2019 · Although chronic respiratory failure can be supported rather effectively with NIV, acute episodes are much more difficult to manage. Generation of adequate cough is vital for mucus clearance during these acute episodes and is often significantly limited in patients with ALS.
6 sty 2012 · Respiratory complications are a common cause of morbidity and mortality in amyotrophic lateral sclerosis (ALS). Treatment of respiratory insufficiency with noninvasive ventilation (NIV) improves ALS patients' quality of life and survival.
