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  1. L27.0 is a billable/specific ICD-10-CM code that can be used to indicate a diagnosis for reimbursement purposes. Short description: Gen skin eruption due to drugs and meds taken internally. The 2025 edition of ICD-10-CM L27.0 became effective on October 1, 2024.

  2. Rashes due to antibiotics are most often morbilliform (exanthematous) or urticarial. It usually takes 7–10 days to become allergic to a drug, so if a reaction is rapid, it is either non-immunological, or it is due to a previous encounter with the same drug or a chemically similar substance.

  3. T36.0X5A is a billable diagnosis code used to specify a medical diagnosis of adverse effect of penicillins, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.

  4. T36.1X5A is a billable diagnosis code used to specify a medical diagnosis of adverse effect of cephalosporins and other beta-lactam antibiotics, initial encounter. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.

  5. L27.0 is a billable diagnosis code used to specify a medical diagnosis of generalized skin eruption due to drugs and medicaments taken internally. The code is valid during the current fiscal year for the submission of HIPAA-covered transactions from October 01, 2024 through September 30, 2025.

  6. Drug-induced urticaria is the term used when urticaria is caused by a drug, most often penicillin, a non-steroidal anti-inflammatory agent (NSAID), or sulfamethoxasole in combination with trimethoprim (see Sulfa drugs and the skin). The drug may be ingested or applied to the skin surface (contact urticaria).

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