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16 gru 2022 · This systematic review aimed to characterise rabies breakthrough infections after the administration of modern cell-culture vaccines, and to identify educational and clinical interventions that might prevent future cases.
1 sty 2023 · Rabies is a zoonotic and progressive viral disease in warm-blooded animals including human that is almost always fatal following the onset of clinical symptoms. Increasing evidence indicated that vaccination is an effective strategy for preventing rabies in the host reservoir.
2 cze 2021 · KEDRAB was evaluated in a two-center, open-label clinical trial in 30 pediatric patients exposed or possibly exposed to rabies virus for whom post-exposure prophylaxis (PEP) was indicated.
23 wrz 2017 · Vaccines based on mRNA coding for antigens have been shown to be safe and immunogenic in preclinical models. We aimed to report results of the first-in-human proof-of-concept clinical trial in healthy adults of a prophylactic mRNA-based vaccine encoding rabies virus glycoprotein (CV7201).
Blood samples were tested by the China Food and Drug Testing Institute with the Rapid Fluorescent Focus Inhibition Test (RFFIT) to detect rabies virus antibody levels. Citation 12, Citation 13. Based on the WHO criteria, the rabies virus neutralizing antibody (RVNA) concentration ≥ 0.5IU/mL was considered as adequate.
3 paź 2019 · This paper summarizes the particular criteria that the SAGE Working Group and WHO personnel reviewed as part of the evaluation process for recommending the new one-week intradermal vaccination regimen (2-2-2-0-0) for rabies post-exposure prophylaxis.
23 cze 2017 · The present review describes the etiology of rabies, prevalence and epidemiology, species affected and reservoirs, pathology, immuno pathology and pathogenesis, and advances in diagnosis, vaccination, therapy, management, prevention and control of this important viral pathogen having high public health concerns (Table 1).
