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18 lip 2024 · Children: 5-8 kg: ½ pediatric tablet daily. >8-10 kg: ¾ pediatric tablet daily. >10-20 kg: 1 pediatric tablet daily. >20-30 kg: 2 pediatric tablets daily. >30-40 kg 3 pediatric tablets daily. >40 kg and over: 1 adult tablet daily. Chloroquine. Begin 1 – 2 weeks before travel, once/week during travel, and for 4 weeks after leaving.
20 sie 2008 · Until more evidence emerges, children with severe malaria can be treated with either quinine, artesunate or artemether, but, of these three, the authors prefer water‐soluble artesunate. The artemisinin derivatives are more effective, safer, and also easier to use than quinine.
2 lut 2022 · The study found no evidence to support the use of a 3-day low dose course of quinine plus clindamycin in the treatment of uncomplicated falciparum malaria in children under 5 years of age in Kenya, where artemether-lumefantrine is still effective.
1 cze 2022 · Severe or complicated malaria in children should be treated with intravenous artesunate or intravenous quinine if artesunate is not available. Children with severe malaria should be managed in a high-dependency or intensive care setting.
4 gru 2019 · For the treatment of malaria in children, paediatric dosing recommendations for several agents, including parenteral artesunate and dihydroartemisinin–piperaquine, have belatedly been shown to be suboptimal.
For quinine-based regimens, doxycycline or tetracycline should be used only in children aged ≥8 years. An alternative for children aged ≥8 years is clindamycin 7 mg/kg body weight per dose by mouth given every 8 hours.
Severe malaria results in over a million deaths every year, most of them in children aged under five years and living in sub‐Saharan Africa. This review examines whether treatment with artesunate, instead of the standard treatment quinine, would result in fewer deaths and better treatment outcomes.
