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16 wrz 2024 · This systematic review and meta-analysis found that reactions to direct penicillin challenges may be infrequent across a variety of patient populations and protocols, suggesting that penicillin challenges may be safe for incorporation into routine penicillin allergy delabeling efforts.
In the United States, patients commonly report having a penicillin allergy, with penicillin being the most frequent beta-lactam allergy. However, very few patients experience a clinically significant immune-mediated allergic reaction to penicillin.
27 sty 2021 · Analysis of the studies included in the review demonstrates that in patients assessed as having a low risk of true allergy to penicillin, based on their allergy history, direct oral challenge can be carried out safely and is effective for de-labelling patients with unverified allergy labels.
10 lip 2024 · This article outlines recent developments in non-allergist delivered penicillin allergy de-labelling (PADL), discusses remaining controversies and uncertainties and explores the future for non...
14 paź 2024 · The dissemination of findings from this knowledge synthesis to various stakeholders is intended to inform on options for evidence-based interventions to aid in delabeling penicillin allergies in individuals with a low risk of experiencing a hypersensitivity reaction.
15 sty 2019 · Evaluation of penicillin allergy before deciding not to use penicillin or other β-lactam antibiotics is an important tool for antimicrobial stewardship. Many patients report they are allergic to penicillin but few have clinically significant reactions.
7 gru 2021 · CMA and egg allergy are the most common food allergies early in life, with an estimated prevalence in developed countries of 2.5% for milk and 1.3% for egg allergy, at age 1 year . CMA is commonly reported by parents, in up to 14% of young children [ 36 ].
