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25 lis 2021 · All experimental GO annotations for proteins in the tree are overlaid on the tree, and an expert uses a variety of information to identify branches where functions were most likely gained and lost; this information includes the phylogenetic tree (especially gene duplication events), taxonomic groups, and presence/absence of protein domains and ...
The PANTHER knowledgebase can be downloaded or accessed via an extensive API. In addition, PANTHER provides software tools to facilitate the application of the knowledgebase to common protein sequence analysis tasks: exploring an annotated genome by gene function; performing “enrichment analysis.
8 lis 2018 · We have created a completely new PANTHER GO-slim and associated annotations, and improved the PANTHER Protein Class for protease and protease inhibitor families. In the gene list analysis tools, we have developed additional software to enable users to easily analyze lists from over 900 genomes (up from 104 in our last update).
8 gru 2020 · Other improvements include additional plant genomes and an updated PANTHER GO-slim. Coverage of protein-coding genes by PANTHER evolutionary and clade-level annotations.
8 wrz 2024 · Tools to curate, browse, search, visualize and download both the ontology and annotations. Includes bioinformatic guides (Notebooks) and simple API access to integrate the GO into your research.
30 paź 2021 · In addition to the 142 organisms in PANTHER trees, we provide precalculated PANTHER family/subfamily and GO annotations for over 1,000 other whole reference proteomes from UniProt.
17 lis 2015 · Gene annotations, iTAG3.2 gene ontology (GO) terms, were obtained from the PANTHER classification system version 10 (Mi et al., 2016). GO enrichment analysis was performed for GO Biological...