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21 lip 2022 · In some cases, elevated levels of niacin can lead to moderate to severe liver damage. When this occurs, it can cause liver failure, which can result in death.
9 lip 2020 · Niacin can cause mild-to-moderate serum aminotransferase elevations and high doses and certain formulations of niacin have been linked to clinically apparent, acute liver injury which can be severe as well as fatal.
Signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes. Muscle pain or weakness. Chest pain or pressure.
3 wrz 2024 · Safety considerations: Rash, stomach upset, elevated liver enzymes (at more than 3 grams (g) per day, though this is rare), thrombocytopenia (in people who have renal disease and are on dialysis). Niacinamide has been studied for several different skin issues. Read on for more information about its possible benefits.
17 paź 2024 · Side effects of niacin. Niacin is water-soluble, meaning excess amounts come out in your urine. Still, taking high-dose niacin supplements can cause side effects, including:
High doses of niacin cause: A time-release form of niacin reduces flushing. But long-term use is associated with liver damage. In addition, niacin can interact with other cholesterol-lowering medicines. You should not take niacin at high doses without your doctor's supervision.
Liver disease: Taking high doses of niacin might increase liver damage. Don't use large amounts if you have liver disease.
