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1 wrz 2012 · Causes of neutrophilia: constitutional (hereditary neutrophilia, familial cold urticaria, leukocyte adhesion deficiency) and acquired (bacterial infections, chronic Epstein-Barr virus infection, cytokine therapy, eosinophilia myalgia syndrome)
3 paź 2020 · Objectives: Select the most relevant diagnostic tests to determine the specific cause of neutropenia in different clinical scenarios. Differentiate between primary and secondary causes of neutropenia, focusing on bone marrow production versus extramedullary causes.
6 wrz 2024 · Neutropenia refers to a decrease in circulating neutrophils, which for adults corresponds to <1500 cells/microL in most clinical laboratories. This topic discusses the evaluation of the adult patient with unexplained neutropenia.
This article outlines an algorithm-based approach to classify neutropenia based on clinical, hematologic, and molecular genetic features. It covers the causes, diagnosis, and differential diagnosis of various disorders resulting in neutropenia, such as infections, autoimmune diseases, and malignancies.
30 mar 2023 · Five main topics were identified: (1) definition and classification of neutropenias, (2) diagnostic approach, (3) natural history and follow-up, (4) treatment, and (5) special situations, and a number of key questions were formulated for each topic.
Neutropenia is defined as a total NEU count less than 2 x 109/l in adults. Complications are associated to the depth of neutropenia. Only patients with a NEU count < 1 x 109/l need review by Haematology; a NEU count < 0.5 is associated with a major infection risk. NEU < 1 associated with:
21 paź 2016 · Increased numbers of cells. Increases affecting more than one cell line. A simultaneous increase in the cells of more than one cell line suggests overproduction of cells originating in an early precursor cell.
